Comunicazione

Spin field theory for neuronal signaling.

Zangari del Balzo G.
  Mercoledì 28/09   16:30 - 19:00   Edificio Psicologia 2 - Aula 2C   V - Biofisica e Fisica medica
Neuronal signaling processes, usually described on the basis of "HH" (Hodgkin-Huxley) models, could be interpreted today from a new point of view, based on a strict biophysical consistency of the molecular processes underlying the generation of action potentials. Here, generation and transport of action potentials are intimately modeled and linked to the functional molecular dynamics of voltage-gated ion channels present on the axonal membrane of nerve cells. Therefore we suggest a field theory of voltage-gated ion channels in patches of the membrane of nerve cells. Action potentials are interpreted as particles of the field equation for the Hamiltonian. This formalism could open the way to the development of many applications, from neurology to artificial intelligence and quantum computing. Moreover, it is possible to make up new algorithms useful to functional magnetic resonance (MRI) in order to investigate neurodegenerative and demyelinating diseases, such as Alzheimer's, Multiple Sclerosis, Stroke and ALS.